Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 13/20 | 0.64 |
| ▸ | FBP1 | P09467 | 2/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.58 |
| ▸ | KDR | P35968 | 5/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.51 |
| ▸ | KIF5B | P33176 | 1/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.51 |
| ▸ | FLT1 | P17948 | 1/20 | 0.51 |
| ▸ | FLT4 | P35916 | 1/20 | 0.51 |
| ▸ | GAK | O14976 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30820490 | 0.91 | EGFR (0.76) | EGFRFBP1ABCG2KDRRET | |
| SCHEMBL4578533 | 0.89 | KDR (0.65) | EGFRFBP1KDRRETKIF5B | |
| SCHEMBL30820511 | 0.85 | EGFR (0.64) | EGFRFBP1ABCG2KDRRET | |
| SCHEMBL30820491 | 0.84 | EGFR (0.63) | EGFRFBP1ABCG2KDRRET | |
| SCHEMBL29168705 | 0.84 | EGFR (0.63) | EGFRFBP1ABCG2KDRRET | |
| SCHEMBL30820443 | 0.84 | EGFR (0.63) | EGFRFBP1ABCG2KDRRET | |
| SCHEMBL30820600 | 0.83 | FBP1 (0.62) | EGFRFBP1ABCG2KDRRET | |
| SCHEMBL29168723 | 0.83 | FBP1 (0.62) | EGFRFBP1ABCG2KDRRET | |
| SCHEMBL1468038 | 0.80 | KDR (0.77) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL16212500 | 0.80 | KDR (0.57) | EGFRABCG2KDRRETFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693505-A | Heteroaryl derivative compounds and uses thereof | 沃若诺伊公司 | 2024-03-12 | — | — | CN | disclosed |