Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844155 | 0.81 | MAPK1 (0.50) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL16797533 | 0.79 | ESR1 (0.44) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL5246127 | 0.75 | TAAR1 (0.46) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL96177 | 0.73 | MAPK1 (0.55) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL8982011 | 0.73 | KCNN4 (0.47) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL35881 | 0.73 | ESR1 (0.70) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL14910456 | 0.73 | ESR1 (0.70) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| Tert-Butylbenzene SCHEMBL22264599 | 0.73 | MAPK1 (0.55) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| Tert-Butylbenzene SCHEMBL22264597 | 0.73 | MAPK1 (0.55) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| Tert-Butylbenzene SCHEMBL18889 | 0.73 | MAPK1 (0.55) | MAPK1ALDH1A1TAAR1ALOX15ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850548-A | Preparation method of cycloolefin copolymer | 中国化学赛鼎宁波工程有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-109206556-A | A kind of amine-containing organolithium preparation functionalization butadiene-styrene rubber | 中绿新材料（江苏）有限公司 | 2019-01-15 | — | — | CN | claimed |
| EP-0402974-B1 | Preparation of alkyl methacrylate monomers for anionic polymerization | SHELL INT RESEARCH (NL) | 1995-09-06 | — | — | EP | claimed |
| CN-115572341-B | Functionalized polyolefin elastomer and preparation method thereof | 大连万慷工业科技有限公司 | 2024-04-23 | — | — | CN | disclosed |
| CN-116731227-A | Preparation method of alpha-olefin oligomer for synthetic lubricating oil base oil | 大连理工大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-115850548-A | Preparation method of cycloolefin copolymer | 中国化学赛鼎宁波工程有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115572341-A | Functionalized polyolefin elastomer and preparation method thereof | 大连万慷工业科技有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-111087508-A | Coordination chain transfer polyisoprene system based on amidino rare earth alkyl compound | 复旦大学 | 2020-05-01 | — | — | CN | disclosed |
| EP-3452518-A1 | RUBBER MIXTURE, VULCANIZATE OF THE RUBBER MIXTURE, AND VEHICLE TIRES | Continental Reifen Deutschland GmbH (DE) | 2019-03-13 | — | — | EP | disclosed |
| CN-109206556-A | A kind of amine-containing organolithium preparation functionalization butadiene-styrene rubber | 中绿新材料（江苏）有限公司 | 2019-01-15 | — | — | CN | disclosed |
| US-7794632-B2 | Process for the preparation of pure aryllithium compounds and their use | CHEMETALL GMBH (DE) | 2010-09-14 | — | — | US | disclosed |
| US-20030155665-A1 | Process for the preparation of pure aryllithium compounds and their use | CHEMETALL GMBH (DE) | 2003-08-21 | — | — | US | disclosed |
| EP-1295887-A1 | Preparation of pure aryl lithium compounds and their use | Chemetall GmbH (DE) | 2003-03-26 | — | — | EP | disclosed |
| EP-1085029-A1 | Process for polymerizing a methacrylic ester or an acrylic ester | KURARAY CO., LTD. (JP) | 2001-03-21 | — | — | EP | disclosed |
| EP-1051461-A2 | FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE | ORR, William C. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999066009-A2 | FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE | ORR WILLIAM C (US) | 1999-12-23 | — | — | WO | disclosed |
| EP-0954558-A1 | FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY | ORR, William C. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1998026028-A1 | FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY | ORR WILLIAM C (US) | 1998-06-18 | — | — | WO | disclosed |
| US-5171467-A | Reacting two moles of alkali metal with one mole of organic halide and anhydrous magnesium halide in liquid hydrocarbon solvent containing Lewis base | FMC CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |
| US-4254238-A | Hydrocarbon/ethylene oxide random graft copolymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030155665-A1 | Process for the preparation of pure aryllithium compounds and their use | TYR, MLLT3, MLLT1 | MAPK1 749/4885ALDH1A1 3105/4885TAAR1 704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.