Tert-Butylbenzene

Tert-Butylbenzene

SCHEMBL18889

CC(C)(C)c1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.55
TSHR P16473 3/20 0.53
ALDH1A1 P00352 3/20 0.50
TAAR1 Q96RJ0 1/20 0.50
LMNA P02545 1/20 0.50
TYR P14679 1/20 0.50
ALOX15 P16050 1/20 0.50
ESR1 P03372 2/20 0.48
ESR2 Q92731 2/20 0.48
CYP3A4 P08684 1/20 0.48
KCNN4 O15554 3/20 0.48
MAPT P10636 2/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
CYP2C19 P33261 1/20 0.44
HIF1A Q16665 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tert-Butylbenzene SCHEMBL2568053 1.00 MAPK1 (0.55) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL22264597 1.00 MAPK1 (0.55) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL337648 1.00 MAPK1 (0.55) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL22264599 1.00 MAPK1 (0.55) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL16583175 0.97 MAPK1 (0.52) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL309340 0.97 LMNA (0.55) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL11852689 0.97 MAPK1 (0.52) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL975494 0.97 MAPK1 (0.52) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL6537004 0.97 MAPK1 (0.52) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL5921915 0.97 MAPK1 (0.52) MAPK1TSHRALDH1A1TAAR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 23613 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116947907-B Boron-nitrogen compound and preparation method and application thereof Jihua Hengye (Foshan) Electronic Materials Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-118117169-B Special additive for electrolyte, electrolyte and lithium ion battery TIANMU LAKE INSTITUTE OF ADVANCED ENERGY STORAGE TECHNOLOGIES Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-116947908-B Boron-nitrogen compound and preparation method and application thereof Jihua Hengye (Foshan) Electronic Materials Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-113788745-B Preparation method of convaldehyde 万华化学集团股份有限公司 2026-05-19 CN claimed
CN-122037340-A Rubber composite material with marine antifouling property and preparation method and application thereof 辽宁维航基业科技有限公司 2026-05-15 CN claimed
CN-122037049-A Zwitterionic modified copolymer and preparation method thereof, zwitterionic copolymer coating and rubber composite material 北京化工大学 2026-05-15 CN claimed
CN-122037723-A Hydrophobic heat insulation material containing aerogel additive and preparation method thereof 赢胜节能集团股份有限公司 2026-05-15 CN claimed
CN-122036463-A Method for preparing phenolic compound from alkylbenzene 中国科学院大连化学物理研究所 2026-05-15 CN claimed
CN-122005927-A Decellularized scaffold composite dynamic hydrogel material, preparation method and application thereof 华南理工大学 2026-05-12 CN claimed
CN-122010914-A Quinazoline-coumarin compound and preparation method and application thereof 郑州大学 2026-05-12 CN claimed
US-4130586-A Process for producing imine compounds MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1978-12-19 US claimed
US-4108681-A AROMATIC SOLVENT HAVING HIGH FLASH POINT AND A FUSED HETEROCYCLIC RING COMPOUND HALLIBURTON COMPANY (US) 1978-08-22 US claimed
US-4083869-A REACTING BENZOPHENONE WITH AMMONIA IN PRESENCE OF METAL OXIDE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1978-04-11 US claimed
US-4046827-A POROUS ACID-ACTIVE ZEOLITE CATALYST MOBIL OIL CORPORATION (US) 1977-09-06 US claimed
US-4033784-A Method for dissolving asphaltic material HALLIBURTON COMPANY (US) 1977-07-05 US claimed
US-4024076-A Process for producing granular sulfurized material, granular carbon or granular activated carbon MARUZEN OIL CO. LTD. (JA) 1977-05-17 US claimed
US-4020102-A FROM SODIUM B-NAPHTHOLATE AND CARBON DIOXIDE BASF AKTIENGESELLSCHAFT (DT) 1977-04-26 US claimed
US-3981961-A Method of selective stripping of plutonium from organic solvents loaded with plutonium COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1976-09-21 US claimed
US-3954880-A EMULSIFICATION, CRYSTALLIZATION NIPPON OIL AND FATS CO., LTD. (JA) 1976-05-04 US claimed
US-3953596-A 8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals ICI UNITED STATES INC. (US) 1976-04-27 US claimed