Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30822013 | 0.89 | ACKR3 (0.49) | CYP1A2CYP2C9CYP2C19ACKR3KDM4E | |
| SCHEMBL3680133 | 0.83 | HTR2C (0.67) | KDM4EALDH1A1HTR2CHTR2ASLC6A4 | |
| SCHEMBL3688963 | 0.83 | HRH4 (0.67) | KDM4EGRM4HTR2CHRH4RAB9A | |
| Hydrochloric Acid SCHEMBL8597079 | 0.81 | HTR2C (0.65) | KDM4EALDH1A1HTR2CHTR2ASLC6A4 | |
| SCHEMBL30600701 | 0.80 | GRM4 (0.52) | ACKR3KDM4ETSHRGRM4LMNA | |
| SCHEMBL3688922 | 0.79 | ACKR3 (0.52) | CYP1A2CYP2C19ACKR3TSHRLMNA | |
| SCHEMBL9673340 | 0.79 | HTR2A (0.71) | KDM4ETSHRALDH1A1LMNATDP1 | |
| SCHEMBL4766806 | 0.79 | HRH4 (0.71) | KDM4ETSHRALDH1A1GLAGAA | |
| SCHEMBL27643484 | 0.77 | HRH4 (0.69) | KDM4ETSHRALDH1A1GLAGAA | |
| SCHEMBL29746904 | 0.76 | HTR2A (0.73) | KDM4ETSHRALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240043439-A1 | COMPOUNDS AS C5AR INHIBITORS | KIRA PHARMACEUTICALS (SUZHOU) LTD. (CN) | 2024-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240043439-A1 | COMPOUNDS AS C5AR INHIBITORS | C5AR1, C5AR2, C3AR1 | CYP1A2 2787/4885CYP2C9 1112/4885CYP2C19 1155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.