Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | GALK1 | P51570 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30822685 | 0.80 | CHEK1 (0.39) | KMT2AHSD17B10KDM4E | |
| SCHEMBL30822734 | 0.80 | TYMS (0.35) | PARP1APOBEC3G | |
| SCHEMBL30822664 | 0.78 | CYP1A2 (0.37) | KMT2APARP1PRKD3PRKACAPRKCQ | |
| SCHEMBL4382672 | 0.78 | PARP1 (0.41) | GAABLMKMT2AHSD17B10SAE1 | |
| SCHEMBL1840156 | 0.77 | CDC7 (0.49) | PRKD3PRKCGPRKCBPRKCAPRKACA | |
| SCHEMBL30822687 | 0.77 | JAK2 (0.39) | GAAKMT2AHSD17B10PARP1KDM4E | |
| SCHEMBL30822732 | 0.77 | PARP1 (0.33) | PARP1 | |
| SCHEMBL30822724 | 0.77 | CYP1A2 (0.35) | KMT2AHSD17B10PARP1KDM4EALDH1A1 | |
| SCHEMBL30822708 | 0.75 | AURKA (0.41) | GAAKDM4EALDH1A1 | |
| SCHEMBL28557365 | 0.74 | GAA (0.51) | GAAKMT2AKDM4EMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659001-A | Aminopyrimidine derivatives and their use in medicine | 广东东阳光药业股份有限公司 | 2024-03-08 | — | — | CN | disclosed |