Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 3/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.34 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30822734 | 0.83 | TYMS (0.35) | CDC7CDK2ROCK1PIM1TYMS | |
| SCHEMBL30822643 | 0.80 | GAA (0.38) | KDM4EHSD17B10KMT2A | |
| SCHEMBL30822718 | 0.78 | TYMS (0.39) | CHEK1RXFP1CDC7CDK2ROCK1 | |
| SCHEMBL28553902 | 0.75 | MAT2A (0.45) | CDC7CDK2ROCK1MAP3K14HSD17B10 | |
| SCHEMBL30822664 | 0.73 | CYP1A2 (0.37) | CHEK1PIM1TYMSDYRK1AKDM4E | |
| SCHEMBL30822687 | 0.72 | JAK2 (0.39) | RXFP1CA12CA9KDM4EHTT | |
| SCHEMBL28580312 | 0.72 | BIRC5 (0.44) | KDM4ELMNAHTTL3MBTL1KMT2A | |
| SCHEMBL30034125 | 0.72 | BIRC5 (0.44) | KDM4ELMNAHTTL3MBTL1KMT2A | |
| SCHEMBL30822715 | 0.70 | EGFR (0.33) | — | |
| SCHEMBL30822669 | 0.70 | JAK2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659001-A | Aminopyrimidine derivatives and their use in medicine | 广东东阳光药业股份有限公司 | 2024-03-08 | — | — | CN | disclosed |