Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GRK2 | P25098 | 2/20 | 0.42 |
| ▸ | GRK1 | Q15835 | 2/20 | 0.42 |
| ▸ | GRK5 | P34947 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377227 | 0.79 | RAB9A (0.76) | RAB9AMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL9953323 | 0.79 | RAB9A (0.76) | RAB9AMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL30557125 | 0.78 | HTT (0.61) | RAB9ASMN1; SMN2POLBKDM4EHTT | |
| SCHEMBL30822653 | 0.78 | PIK3CD (0.42) | RAB9AMEN1KMT2ASMN1; SMN2GRK2 | |
| Hydrochloric Acid SCHEMBL30437013 | 0.78 | RAB9A (0.73) | RAB9AMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL30516941 | 0.76 | RAB9A (0.61) | RAB9AMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL15228845 | 0.76 | RAB9A (0.61) | RAB9AMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL16291434 | 0.74 | RAB9A (0.72) | RAB9AMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL20886926 | 0.74 | RAB9A (0.72) | RAB9AMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL20886963 | 0.74 | RAB9A (1.00) | RAB9AMEN1KMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659001-A | Aminopyrimidine derivatives and their use in medicine | 广东东阳光药业股份有限公司 | 2024-03-08 | — | — | CN | disclosed |