Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 3/20 | 0.34 |
| ▸ | IDO2 | Q6ZQW0 | 3/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29164790 | 1.00 | TDO2 (0.34) | TDO2IDO2IDO1PIK3CDPIK3R1 | |
| SCHEMBL29164785 | 1.00 | TDO2 (0.34) | TDO2IDO2IDO1PIK3CDPIK3R1 | |
| SCHEMBL30822680 | 0.90 | SYK (0.41) | TDO2IDO2IDO1PIK3CDPIK3R1 | |
| SCHEMBL29164556 | 0.90 | SYK (0.41) | TDO2IDO2IDO1PIK3CDPIK3R1 | |
| SCHEMBL29164558 | 0.90 | SYK (0.41) | TDO2IDO2IDO1PIK3CDPIK3R1 | |
| SCHEMBL30822725 | 0.84 | PIM1 (0.35) | TDO2IDO2IDO1PIK3CDPIK3R1 | |
| SCHEMBL29164524 | 0.84 | PIM1 (0.35) | TDO2IDO2IDO1PIK3CDPIK3R1 | |
| SCHEMBL29164527 | 0.84 | PIM1 (0.35) | TDO2IDO2IDO1PIK3CDPIK3R1 | |
| SCHEMBL30822713 | 0.80 | PIK3R1 (0.41) | PIK3CDPIK3R1PIK3CAPIK3CG | |
| SCHEMBL29164722 | 0.80 | PIK3R1 (0.41) | PIK3CDPIK3R1PIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659001-A | Aminopyrimidine derivatives and their use in medicine | 广东东阳光药业股份有限公司 | 2024-03-08 | — | — | CN | disclosed |