Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29165008 | 1.00 | HDAC1 (0.48) | HDAC1HDAC8HDAC6NPC1RAB9A | |
| SCHEMBL30822684 | 0.81 | NPC1 (0.64) | HDAC1HDAC8HDAC6NPC1RAB9A | |
| SCHEMBL29164752 | 0.81 | NPC1 (0.64) | HDAC1HDAC8HDAC6NPC1RAB9A | |
| SCHEMBL696231 | 0.80 | NPC1 (0.56) | NPC1RAB9AALOX15HTTMAPT | |
| SCHEMBL3418472 | 0.77 | RXFP1 (0.57) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL6498338 | 0.76 | ALDH1A1 (0.38) | MAPTALDH1A1LMNA | |
| SCHEMBL30822730 | 0.75 | PDE10A (0.51) | NPC1RAB9ASORT1MAPT | |
| SCHEMBL29164864 | 0.75 | PDE10A (0.51) | NPC1RAB9ASORT1MAPT | |
| SCHEMBL3421073 | 0.74 | NPC1 (0.63) | NPC1RAB9AALDH1A1KCNMA1 | |
| SCHEMBL6498335 | 0.74 | GAA (0.57) | NPC1RAB9AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659001-A | Aminopyrimidine derivatives and their use in medicine | 广东东阳光药业股份有限公司 | 2024-03-08 | — | — | CN | disclosed |