Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 10/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29164749 | 1.00 | PIK3CD (0.35) | PIK3CDPIK3CBSYKPIK3CGCHEK1 | |
| SCHEMBL29164747 | 1.00 | PIK3CD (0.35) | PIK3CDPIK3CBSYKPIK3CGCHEK1 | |
| SCHEMBL29164788 | 0.84 | PIK3CD (0.35) | PIK3CDPIK3CBPIK3CGPIK3R1PIK3CA | |
| SCHEMBL29164791 | 0.84 | PIK3CD (0.35) | PIK3CDPIK3CBPIK3CGPIK3R1PIK3CA | |
| SCHEMBL30822648 | 0.84 | PIK3CD (0.35) | PIK3CDPIK3CBPIK3CGPIK3R1PIK3CA | |
| SCHEMBL30822729 | 0.81 | PIK3CD (0.40) | PIK3CDPIK3CBPIK3CGPIK3R1PIK3CA | |
| SCHEMBL29164550 | 0.81 | PIK3CD (0.40) | PIK3CDPIK3CBPIK3CGPIK3R1PIK3CA | |
| SCHEMBL29164551 | 0.81 | PIK3CD (0.40) | PIK3CDPIK3CBPIK3CGPIK3R1PIK3CA | |
| SCHEMBL14649467 | 0.78 | PIK3CD (0.43) | PIK3CDPIK3CBPIK3CGKDM4EPIK3R1 | |
| SCHEMBL29164734 | 0.78 | PIK3CD (0.37) | PIK3CDPIK3CBSYKPIK3CGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659001-A | Aminopyrimidine derivatives and their use in medicine | 广东东阳光药业股份有限公司 | 2024-03-08 | — | — | CN | disclosed |