Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 17/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | PIK3R2 | O00459 | 8/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29164550 | 1.00 | PIK3CD (0.40) | PIK3CDPIK3CGPIK3R1PIK3CBABCB11 | |
| SCHEMBL29164551 | 1.00 | PIK3CD (0.40) | PIK3CDPIK3CGPIK3R1PIK3CBABCB11 | |
| SCHEMBL29164574 | 0.89 | CYP1A2 (0.38) | PIK3CDPIK3CGPIK3R1PIK3CBABCB11 | |
| SCHEMBL30822689 | 0.89 | CYP1A2 (0.38) | PIK3CDPIK3CGPIK3R1PIK3CBABCB11 | |
| SCHEMBL29164573 | 0.89 | CYP1A2 (0.38) | PIK3CDPIK3CGPIK3R1PIK3CBABCB11 | |
| SCHEMBL29164896 | 0.88 | PIK3CD (0.40) | PIK3CDPIK3CGPIK3R1PIK3CBABCB11 | |
| SCHEMBL30822727 | 0.88 | PIK3CD (0.40) | PIK3CDPIK3CGPIK3R1PIK3CBABCB11 | |
| SCHEMBL29164895 | 0.88 | PIK3CD (0.40) | PIK3CDPIK3CGPIK3R1PIK3CBABCB11 | |
| SCHEMBL29164675 | 0.87 | PIK3CD (0.40) | PIK3CDPIK3CGPIK3R1PIK3CBABCB11 | |
| SCHEMBL29164734 | 0.87 | PIK3CD (0.37) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659001-A | Aminopyrimidine derivatives and their use in medicine | 广东东阳光药业股份有限公司 | 2024-03-08 | — | — | CN | disclosed |