Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 4/20 | 0.67 |
| ▸ | CLK2 | P49760 | 4/20 | 0.67 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.67 |
| ▸ | CDK2 | P24941 | 13/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.53 |
| ▸ | CDK1 | P06493 | 5/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 2/20 | 0.45 |
| ▸ | CCNE2 | O96020 | 7/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 7/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30822737 | 0.93 | CLK1 (0.58) | CLK1CLK2CLK4CDK2CCNE1 | |
| SCHEMBL20028287 | 0.81 | CLK1 (1.00) | CLK1CLK2CLK4CDK2CCNE1 | |
| SCHEMBL20028640 | 0.81 | CLK1 (1.00) | CLK1CLK2CLK4CDK2CCNE1 | |
| SCHEMBL20028290 | 0.81 | CLK1 (1.00) | CLK1CLK2CLK4CDK2CCNE1 | |
| SCHEMBL30822750 | 0.81 | FLT3 (0.57) | CDK2CCNE1CDK1CCNB1FLT3 | |
| SCHEMBL31707903 | 0.77 | CLK1 (0.56) | CLK1CLK2CLK4CDK2CCNE1 | |
| Hydrochloric Acid SCHEMBL31707881 | 0.76 | CLK1 (0.55) | CLK1CLK2CLK4CDK2CCNE1 | |
| SCHEMBL20027792 | 0.76 | CLK1 (0.79) | CLK1CLK2CLK4CDK2CCNE1 | |
| SCHEMBL20028201 | 0.76 | CLK1 (0.79) | CLK1CLK2CLK4CDK2CCNE1 | |
| SCHEMBL20027793 | 0.76 | CLK1 (0.79) | CLK1CLK2CLK4CDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659016-A | Cyclin modulators | 嘉兴优博生物技术有限公司 | 2024-03-08 | — | — | CN | disclosed |