Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.57 |
| ▸ | CDK2 | P24941 | 18/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 17/20 | 0.56 |
| ▸ | CDK1 | P06493 | 4/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.56 |
| ▸ | CCNE2 | O96020 | 14/20 | 0.54 |
| ▸ | CCNA2 | P20248 | 14/20 | 0.54 |
| ▸ | CCNA1 | P78396 | 14/20 | 0.54 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CDK7 | P50613 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | CCNH | P51946 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30822737 | 0.82 | CLK1 (0.58) | FLT3CDK2CCNE1CDK1CCNB1 | |
| SCHEMBL30822749 | 0.81 | CLK1 (0.67) | FLT3CDK2CCNE1CDK1CCNB1 | |
| SCHEMBL20549659 | 0.77 | CDK2 (0.61) | FLT3CDK2CCNE1CDK1CCNB1 | |
| SCHEMBL20549660 | 0.77 | CDK2 (0.61) | FLT3CDK2CCNE1CDK1CCNB1 | |
| SCHEMBL27139782 | 0.76 | CCNE2 (0.90) | CDK2CCNE1CCNE2CCNA2CCNA1 | |
| SCHEMBL6824057 | 0.76 | FLT3 (0.58) | FLT3CDK2CCNE1CDK1CCNB1 | |
| SCHEMBL6824059 | 0.76 | FLT3 (0.58) | FLT3CDK2CCNE1CDK1CCNB1 | |
| SCHEMBL22571127 | 0.76 | CDK2 (0.67) | CDK2CCNE1CDK1CCNB1CCNE2 | |
| SCHEMBL23547294 | 0.75 | CDK2 (0.63) | FLT3CDK2CCNE1CDK1CCNB1 | |
| Hydrochloric Acid SCHEMBL6817990 | 0.75 | FLT3 (0.57) | FLT3CDK2CCNE1CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659016-A | Cyclin modulators | 嘉兴优博生物技术有限公司 | 2024-03-08 | — | — | CN | disclosed |