SCHEMBL30822902

SCHEMBL30822902

FC(F)(F)Oc1ccc2nc(Nc3cccc(C(F)(F)F)c3)[nH]c2c1

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RAF1 P04049 4/20 0.60
BRAF P15056 3/20 0.60
KDR P35968 4/20 0.53
TEK Q02763 4/20 0.53
DYRK1A Q13627 1/20 0.52
DYRK1B Q9Y463 1/20 0.52
HTT P42858 1/20 0.50
AURKB Q96GD4 1/20 0.49
CBFB Q13951 2/20 0.46
RUNX1 Q01196 1/20 0.46
TRPV1 Q8NER1 1/20 0.46
PDE10A Q9Y233 1/20 0.44
IDH2 P48735 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30822888 0.89 TRPV1 (0.49) RAF1BRAFKDRTEKDYRK1A
SCHEMBL30822932 0.86 DYRK1A (0.67) RAF1BRAFKDRTEKDYRK1A
SCHEMBL1998475 0.81 AKR1C3 (0.59) RAF1BRAFDYRK1ADYRK1BHTT
SCHEMBL30822892 0.79 HDAC11 (0.60) RAF1BRAFDYRK1ADYRK1BHTT
SCHEMBL30822915 0.77 ALDH1A1 (0.52) RAF1BRAFKDRTEKDYRK1A
SCHEMBL30822904 0.76 CACNA1H (0.45) HTT
SCHEMBL30822901 0.76 DYRK1A (0.67) RAF1BRAFKDRTEKDYRK1A
SCHEMBL4376917 0.76 BRAF (0.59) RAF1BRAFKDRTEKDYRK1A
SCHEMBL20685327 0.74 POLB (0.56) RAF1BRAFKDRHTTCBFB
SCHEMBL30822918 0.74 DYRK1A (0.68) RAF1BRAFKDRTEKDYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042743-A1 SUBSTITUTED BENZIMIDAZOLES FOR TREATING VIRAL DISEASES COUNCIL SCIENT IND RES (IN) 2026-02-12 US claimed
EP-4565566-A1 SUBSTITUTED BENZIMIDAZOLES FOR TREATING VIRAL DISEASES Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) (IN) 2025-06-11 EP claimed
WO-2024028893-A1 SUBSTITUTED BENZIMIDAZOLES FOR TREATING VIRAL DISEASES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) 2024-02-08 WO claimed
US-20260042743-A1 SUBSTITUTED BENZIMIDAZOLES FOR TREATING VIRAL DISEASES COUNCIL SCIENT IND RES (IN) 2026-02-12 US disclosed
EP-4565566-A1 SUBSTITUTED BENZIMIDAZOLES FOR TREATING VIRAL DISEASES Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) (IN) 2025-06-11 EP disclosed
WO-2024028893-A1 SUBSTITUTED BENZIMIDAZOLES FOR TREATING VIRAL DISEASES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) 2024-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042743-A1 SUBSTITUTED BENZIMIDAZOLES FOR TREATING VIRAL DISEASES ACE2, SARS1, NR3C2 RAF1 2027/4885BRAF 3265/4885KDR 675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.