SCHEMBL30823218

SCHEMBL30823218

CCCCC(CC)COC(=O)c1cccc(C(=O)OC[C@H](CC)CCCC)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.73
MAPK1 P28482 3/20 0.73
TSHR P16473 3/20 0.73
CYP3A4 P08684 3/20 0.69
CA2 P00918 1/20 0.69
LMNA P02545 3/20 0.65
HSD17B10 Q99714 1/20 0.65
PRSS1 P07477 1/20 0.62
PRSS2 P07478 1/20 0.62
PRSS3 P35030 1/20 0.62
TDP1 Q9NUW8 2/20 0.53
ATM Q13315 1/20 0.53
RECQL P46063 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
HPGD P15428 1/20 0.44
CYP2C19 P33261 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108377 1.00 ALDH1A1 (0.73) ALDH1A1MAPK1TSHRCYP3A4CA2
SCHEMBL32670285 1.00 ALDH1A1 (0.73) ALDH1A1MAPK1TSHRCYP3A4CA2
SCHEMBL24300536 0.97 ALDH1A1 (0.70) ALDH1A1MAPK1TSHRCYP3A4CA2
SCHEMBL18969812 0.97 ALDH1A1 (0.70) ALDH1A1MAPK1TSHRCYP3A4CA2
SCHEMBL2532026 0.95 ALDH1A1 (0.67) ALDH1A1MAPK1TSHRCYP3A4CA2
SCHEMBL18350999 0.95 TSHR (0.67) ALDH1A1MAPK1TSHRCYP3A4CA2
Isophthalic Acid SCHEMBL7186961 0.95 ALDH1A1 (0.67) ALDH1A1MAPK1TSHRCYP3A4CA2
SCHEMBL27826653 0.95 ALDH1A1 (0.67) ALDH1A1MAPK1TSHRCYP3A4CA2
SCHEMBL3777094 0.94 PRSS1 (0.71) ALDH1A1MAPK1TSHRCYP3A4CA2
SCHEMBL31655552 0.93 ALDH1A1 (0.65) ALDH1A1MAPK1TSHRCYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024030746-A1 RECYCLED CONTENT METAXYLENE AND RELATED CHEMICAL COMPOUNDS FROM WASTE PLASTIC EASTMAN CHEMICAL COMPANY (US) 2024-02-08 WO disclosed