Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700191 | 0.83 | ACHE (0.65) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL17655687 | 0.82 | ACHE (0.50) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12590855 | 0.82 | ACHE (0.59) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13703484 | 0.82 | ACHE (0.58) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL3902756 | 0.82 | ACHE (0.59) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| Ammonia Solution, Strong SCHEMBL28282442 | 0.81 | ACHE (0.63) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7564851 | 0.81 | ACHE (0.76) | ACHE | |
| Hydrochloric Acid SCHEMBL27825731 | 0.81 | ACHE (0.63) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL14094998 | 0.80 | ACHE (0.57) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13741976 | 0.80 | ACHE (0.57) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118843480-A | Polymer-supported 8-sulfonyl-benzazepine compounds and uses thereof | 博尔特生物治疗药物有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-118843481-A | Antibody conjugated 8-sulfonyl-benzazepine compounds and uses thereof | 博尔特生物治疗药物有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-117940168-A | 2-Amino-4-carboxamide-benzazepine immunoconjugates and uses thereof | 博尔特生物治疗药物有限公司 | 2024-04-26 | — | — | CN | disclosed |