Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 5/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8680532 | 0.98 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1SOAT1NR1I2PTPN1 | |
| SCHEMBL8679055 | 0.93 | CYSLTR2 (0.38) | CYSLTR2CYSLTR1SOAT1PTPN1 | |
| SCHEMBL29223147 | 0.92 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1SOAT1PTPN1CSNK1E | |
| SCHEMBL8680609 | 0.86 | ADORA3 (0.37) | SOAT1PTPN1 | |
| SCHEMBL8683347 | 0.83 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1SOAT1PTPN1 | |
| SCHEMBL11692783 | 0.83 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1SOAT1 | |
| SCHEMBL8679017 | 0.82 | ADORA3 (0.41) | — | |
| SCHEMBL8524531 | 0.82 | NR1I2 (0.45) | CYSLTR2CYSLTR1NR1I2CSNK1E | |
| SCHEMBL8683367 | 0.82 | SOAT1 (0.42) | CYSLTR2CYSLTR1SOAT1PTPN1CSNK1E | |
| SCHEMBL984797 | 0.81 | TSHR (0.42) | CYSLTR2CYSLTR1NR1I2CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677334-B | Transient receptor potential MELASTATIN 8 (TRPM 8) antagonists and related methods | 马歇尔大学科研协会 | 2024-04-09 | — | — | CN | disclosed |