Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 4/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679301 | 1.00 | PTPN1 (0.41) | PTPN1SOAT1GCGRNR5A2NR5A1 | |
| SCHEMBL8683367 | 0.98 | SOAT1 (0.42) | PTPN1SOAT1NR5A2NR5A1CSNK1E | |
| SCHEMBL8679272 | 0.95 | PTPN1 (0.39) | PTPN1SOAT1GCGRNR5A2NR5A1 | |
| SCHEMBL15536289 | 0.87 | KDM4E (0.40) | SOAT1ALDH1A1 | |
| SCHEMBL11488024 | 0.85 | KCNH2 (0.40) | PTPN1SOAT1MEN1KMT2ANPSR1 | |
| SCHEMBL11494251 | 0.84 | KCNH2 (0.42) | SOAT1MEN1KMT2ANPSR1 | |
| SCHEMBL6678854 | 0.83 | TSHR (0.43) | SOAT1CSNK1EALDH1A1CNR2CYSLTR2 | |
| SCHEMBL11490645 | 0.83 | KDM4E (0.47) | SOAT1ALDH1A1MEN1KMT2A | |
| SCHEMBL11493367 | 0.83 | MEN1 (0.41) | MEN1KMT2ANPSR1 | |
| SCHEMBL11496182 | 0.83 | HRH1 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677334-B | Transient receptor potential MELASTATIN 8 (TRPM 8) antagonists and related methods | 马歇尔大学科研协会 | 2024-04-09 | — | — | CN | disclosed |