SCHEMBL8679272

SCHEMBL8679272

CCCCC(C)c1ccccc1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.39
SOAT1 P35610 3/20 0.38
POLB P06746 1/20 0.36
NR5A2 O00482 1/20 0.36
NR5A1 Q13285 1/20 0.36
PSMB5 P28074 1/20 0.36
TSHR P16473 2/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
GCGR P47871 1/20 0.35
CYP17A1 P05093 1/20 0.35
CNR2 P34972 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8679301 0.95 PTPN1 (0.41) PTPN1SOAT1NR5A2NR5A1PSMB5
SCHEMBL30823643 0.95 PTPN1 (0.41) PTPN1SOAT1NR5A2NR5A1PSMB5
SCHEMBL8683367 0.93 SOAT1 (0.42) PTPN1SOAT1NR5A2NR5A1ALDH1A1
SCHEMBL15536289 0.89 KDM4E (0.40) SOAT1TSHRKDM4EALDH1A1CA12
SCHEMBL11493367 0.84 MEN1 (0.41)
SCHEMBL11490645 0.84 KDM4E (0.47) SOAT1KDM4EALDH1A1
SCHEMBL11496182 0.84 HRH1 (0.44) ALDH1A1CA12CA1CA2CA9
SCHEMBL11488024 0.83 KCNH2 (0.40) PTPN1SOAT1
SCHEMBL6685019 0.82 TSHR (0.45) SOAT1POLBTSHRKDM4EALDH1A1
SCHEMBL11494251 0.82 KCNH2 (0.42) SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101263203-B Multiple chromophores based on rylene BASF AG 2012-01-11 CN disclosed
CN-101263203-A Multiple chromophores based on rylene BASF AG (DE) 2008-09-10 CN disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed