Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21198563 | 1.00 | LPAR1 (0.61) | LPAR1POLBMEN1KMT2ARXFP1 | |
| SCHEMBL19643985 | 0.86 | LPAR1 (0.60) | LPAR1POLBMEN1KMT2ARXFP1 | |
| SCHEMBL31079121 | 0.83 | LPAR1 (0.57) | LPAR1POLBMEN1KMT2ARXFP1 | |
| SCHEMBL3504431 | 0.83 | LPAR1 (0.57) | LPAR1POLBMEN1KMT2ALMNA | |
| SCHEMBL2076016 | 0.83 | LPAR1 (0.57) | LPAR1POLBMEN1KMT2ARXFP1 | |
| SCHEMBL29475122 | 0.83 | LPAR1 (0.57) | LPAR1POLBMEN1KMT2ALMNA | |
| SCHEMBL14350894 | 0.82 | ALDH1A1 (0.69) | LPAR1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL31630583 | 0.79 | LPAR1 (0.53) | LPAR1POLBMEN1KMT2ARXFP1 | |
| SCHEMBL21217705 | 0.79 | HTT (0.72) | LPAR1MEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL4193257 | 0.78 | ALDH1A1 (0.55) | LPAR1POLBMEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655681-B | Heterocyclylamino-substituted triazoles as modulators of Rho-related protein kinases | 莱德克斯制药公共有限公司 | 2024-01-05 | — | — | CN | disclosed |