Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 17/20 | 0.75 |
| ▸ | MC5R | P33032 | 1/20 | 0.49 |
| ▸ | MC3R | P41968 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24094660 | 0.87 | MC4R (0.74) | MC4RMC5RMC3RKCNH2ACACB | |
| SCHEMBL31139109 | 0.87 | MC4R (0.74) | MC4RMC5RMC3RKCNH2ACACB | |
| SCHEMBL24094662 | 0.87 | MC4R (0.74) | MC4RMC5RMC3RKCNH2ACACB | |
| SCHEMBL30355172 | 0.85 | MC4R (1.00) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL24094569 | 0.85 | MC4R (1.00) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL30184858 | 0.85 | MC4R (1.00) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL25267222 | 0.85 | MC4R (1.00) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL25583997 | 0.85 | MC4R (1.00) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL24853331 | 0.82 | MC4R (0.72) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL24094702 | 0.82 | MC4R (0.67) | MC4RMC5RMC3RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736205-A | Fused ring compounds as MC4R antagonists, pharmaceutical compositions and their use in medicine | 长春金赛药业有限责任公司 | 2024-03-22 | — | — | CN | disclosed |