Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20600366 | 1.00 | P2RX7 (0.41) | P2RX7TRPV1BRD4CREBBPMAPK1 | |
| SCHEMBL29438283 | 0.90 | BRD4 (0.39) | P2RX7TRPV1BRD4CREBBPMAPK1 | |
| SCHEMBL20600344 | 0.90 | BRD4 (0.39) | P2RX7TRPV1BRD4CREBBPMAPK1 | |
| SCHEMBL20600383 | 0.88 | CNR2 (0.38) | P2RX7TRPV1BRD4CREBBPALDH1A1 | |
| SCHEMBL29438254 | 0.88 | CNR2 (0.38) | P2RX7TRPV1BRD4CREBBPALDH1A1 | |
| SCHEMBL20600363 | 0.86 | MAPK1 (0.40) | P2RX7TRPV1BRD4CREBBPMAPK1 | |
| SCHEMBL30824215 | 0.86 | MAPK1 (0.40) | P2RX7TRPV1BRD4CREBBPMAPK1 | |
| SCHEMBL20621847 | 0.86 | P2RX7 (0.41) | P2RX7TRPV1BRD4CREBBPMAPK1 | |
| SCHEMBL20600149 | 0.86 | P2RX7 (0.41) | P2RX7TRPV1BRD4CREBBPMAPK1 | |
| SCHEMBL30824229 | 0.86 | P2RX7 (0.41) | P2RX7TRPV1BRD4CREBBPMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770227-B | Novel azaquinoline derivatives | 拜耳动物保健有限责任公司 | 2024-03-01 | — | — | CN | disclosed |