Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.45 |
| ▸ | PDE9A | O76083 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15640836 | 0.83 | MEN1 (0.43) | PDE10APDE9AMEN1MAPTKMT2A | |
| SCHEMBL5461270 | 0.81 | HRH1 (0.50) | MEN1MAPTKMT2AHCRTR2 | |
| SCHEMBL21047576 | 0.79 | HCRTR2 (0.44) | PDE10APDE9AMEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL29862885 | 0.79 | HRH1 (0.49) | MEN1MAPTKMT2AHCRTR2 | |
| Hydrochloric Acid SCHEMBL5468114 | 0.79 | HRH1 (0.49) | MEN1MAPTKMT2AHCRTR2 | |
| SCHEMBL29587113 | 0.79 | HCRTR2 (0.44) | PDE10APDE9AMEN1MAPTKMT2A | |
| SCHEMBL21865475 | 0.79 | ESR1 (0.40) | PDE10A | |
| SCHEMBL16874930 | 0.77 | HCRTR2 (0.43) | PDE10APDE9AMEN1MAPTKMT2A | |
| SCHEMBL16874929 | 0.77 | MEN1 (0.41) | PDE10AMEN1MAPTKMT2AHCRTR2 | |
| SCHEMBL16874927 | 0.77 | MEN1 (0.41) | PDE10AMEN1MAPTKMT2AHCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067632-A1 | WEE1 Degrading Compounds and Uses Thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067632-A1 | WEE1 Degrading Compounds and Uses Thereof | WEE1, WEE2, PPME1 | PDE10A 3532/4885PDE9A 3706/4885MEN1 1699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.