Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 3/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | RPS27 | P42677 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.41 |
| ▸ | CSF1R | P07333 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20954 | 1.00 | MAPK8 (0.42) | MAPK8MAPK9MAPK10RPS27MMP13 | |
| SCHEMBL30824684 | 0.91 | MMP13 (0.47) | MMP13ROCK2MAPK1MAOB | |
| SCHEMBL20473 | 0.91 | MMP13 (0.47) | MMP13ROCK2MAPK1MAOB | |
| SCHEMBL20540 | 0.90 | CTNNB1 (0.46) | MAPK8MAPK9MAPK10RPS27ROCK2 | |
| SCHEMBL30824694 | 0.90 | CTNNB1 (0.46) | MAPK8MAPK9MAPK10RPS27ROCK2 | |
| SCHEMBL15478171 | 0.88 | S1PR3 (0.44) | MMP13S1PR3ROCK2HPGDKMT2A | |
| SCHEMBL22027 | 0.86 | S1PR3 (0.42) | S1PR3ROCK2HPGDKMT2AMAOB | |
| SCHEMBL30795220 | 0.86 | S1PR3 (0.42) | S1PR3ROCK2HPGDKMT2AMAOB | |
| SCHEMBL21133 | 0.86 | KDM4E (0.48) | MMP13S1PR3ROCK2MAOBKDM4E | |
| SCHEMBL30794701 | 0.86 | KDM4E (0.48) | MMP13S1PR3ROCK2MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054807-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |