Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.42 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2071931 | 1.00 | KCNQ3 (0.42) | KCNQ3KCNQ2KCNQ4KCNQ5FFAR1 | |
| SCHEMBL2072308 | 0.90 | KLKB1 (0.45) | KCNQ3KCNQ2KCNQ4KCNQ5FFAR1 | |
| SCHEMBL30794647 | 0.90 | KLKB1 (0.45) | KCNQ3KCNQ2KCNQ4KCNQ5FFAR1 | |
| SCHEMBL30795297 | 0.84 | RAB9A (0.39) | KCNQ3KCNQ2KCNQ4KCNQ5FFAR1 | |
| SCHEMBL2069883 | 0.84 | RAB9A (0.39) | KCNQ3KCNQ2KCNQ4KCNQ5FFAR1 | |
| SCHEMBL30795429 | 0.84 | KCNQ3 (0.47) | KCNQ3KCNQ2KCNQ4KCNQ5FFAR1 | |
| SCHEMBL2070740 | 0.84 | SMN1; SMN2 (0.53) | KCNQ3KCNQ2KCNQ4KCNQ5FFAR1 | |
| SCHEMBL2069986 | 0.84 | KCNQ3 (0.47) | KCNQ3KCNQ2KCNQ4KCNQ5FFAR1 | |
| SCHEMBL2070737 | 0.83 | KDR (0.40) | KCNQ3KCNQ2KCNQ4KCNQ5AGPAT2 | |
| SCHEMBL2072313 | 0.83 | CHRM3 (0.45) | FFAR1AGPAT2SMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054807-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |