Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.39 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5848169 | 1.00 | ACKR3 (0.42) | ACKR3CYP3A4GPR55GPR88RORC | |
| SCHEMBL30795863 | 0.87 | CYP3A4 (0.47) | CYP3A4CTSLCTSSCTSKROCK2 | |
| SCHEMBL5849183 | 0.87 | CYP3A4 (0.47) | CYP3A4CTSLCTSSCTSKROCK2 | |
| SCHEMBL30795745 | 0.82 | CHRNA7 (0.55) | CYP3A4GPR88CTSLCTSSCTSK | |
| SCHEMBL5847724 | 0.82 | CHRNA7 (0.55) | CYP3A4GPR88CTSLCTSSCTSK | |
| SCHEMBL5848289 | 0.77 | GPR88 (0.48) | GPR88 | |
| SCHEMBL30794634 | 0.77 | GPR88 (0.48) | GPR88 | |
| SCHEMBL5676107 | 0.76 | CHRNA7 (0.39) | GPR88ROCK2PRKG1 | |
| SCHEMBL30796524 | 0.76 | CHRNA7 (0.39) | GPR88ROCK2PRKG1 | |
| SCHEMBL5849152 | 0.76 | CHRNA7 (0.47) | GPR88ROCK2PRKG1LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054807-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |