Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HHAT | Q5VTY9 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.47 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240992 | 1.00 | HHAT (0.56) | HHATCYP2D6HDAC8HDAC3HDAC1 | |
| SCHEMBL3242938 | 0.93 | CHRM3 (0.55) | HHATCYP2D6HDAC8HDAC3HDAC1 | |
| SCHEMBL30795961 | 0.93 | HHAT (0.54) | HHATCYP2D6HDAC8HDAC3HDAC1 | |
| SCHEMBL30795434 | 0.93 | HHAT (0.52) | HHATCYP2D6HDAC8HDAC3HDAC1 | |
| SCHEMBL30795853 | 0.93 | CHRM3 (0.55) | HHATCYP2D6HDAC8HDAC3HDAC1 | |
| SCHEMBL3236277 | 0.93 | HHAT (0.52) | HHATCYP2D6HDAC8HDAC3HDAC1 | |
| SCHEMBL3232980 | 0.93 | HHAT (0.54) | HHATCYP2D6HDAC8HDAC3HDAC1 | |
| SCHEMBL3236487 | 0.90 | HDAC8 (0.54) | HHATCYP2D6HDAC8HDAC3HDAC1 | |
| SCHEMBL3235146 | 0.90 | CHRM3 (0.52) | HHATCYP2D6HDAC8HDAC3HDAC1 | |
| SCHEMBL3235270 | 0.90 | TRPM8 (0.56) | HHATCYP2D6HDAC8HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054807-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |