Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27391578 | 1.00 | PDE4D (0.46) | PDE4DPDE4BPDE4APDE4CLIMK2 | |
| SCHEMBL30812265 | 0.87 | PDE4D (0.49) | PDE4DPDE4BPDE4APDE4CGPR119 | |
| SCHEMBL31245970 | 0.86 | PDE4D (0.42) | PDE4DPDE4BPDE4APDE4CGPR119 | |
| SCHEMBL30824791 | 0.85 | PDE4D (0.48) | PDE4DPDE4BPDE4APDE4CGPR119 | |
| SCHEMBL30811962 | 0.83 | PDE4D (0.51) | PDE4DPDE4BPDE4APDE4CGPR119 | |
| SCHEMBL30824739 | 0.82 | NOTUM (0.37) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL18165158 | 0.81 | PDE4B (0.52) | PDE4DPDE4BPDE4APDE4CGPR119 | |
| SCHEMBL30011780 | 0.81 | PDE4B (0.52) | PDE4DPDE4BPDE4APDE4CGPR119 | |
| SCHEMBL29054073 | 0.81 | PDE4B (0.52) | PDE4DPDE4BPDE4APDE4CGPR119 | |
| SCHEMBL30811946 | 0.78 | PDE4D (0.47) | PDE4DPDE4BPDE4APDE4CGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054955-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |