Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30824928 | 1.00 | TDP1 (0.48) | TDP1SLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL27392263 | 1.00 | TDP1 (0.48) | TDP1SLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL30812277 | 0.82 | SLC6A4 (0.38) | TDP1SLC6A4KDM1AEP300MAOB | |
| SCHEMBL27391178 | 0.79 | SLC6A4 (0.34) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL30824898 | 0.79 | SLC6A4 (0.34) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL27392262 | 0.78 | TDP1 (0.49) | TDP1SLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL30812128 | 0.78 | TRPV1 (0.33) | SLC6A4KDM1ARBP4EP300HRH3 | |
| SCHEMBL30824822 | 0.77 | BRD4 (0.48) | TDP1KDM1AMAOBITGB3ITGA2B | |
| SCHEMBL27392241 | 0.77 | BRD4 (0.48) | TDP1KDM1AMAOBITGB3ITGA2B | |
| SCHEMBL30824772 | 0.77 | UTS2R (0.34) | SLC6A4PIM1PIM2EP300CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054955-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |