Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 13/20 | 0.48 |
| ▸ | KDM1A | O60341 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27392241 | 1.00 | BRD4 (0.48) | BRD4KDM1ATDP1MAOBITGB3 | |
| SCHEMBL30824839 | 0.82 | BRD4 (0.59) | BRD4KDM1ATDP1 | |
| SCHEMBL30824928 | 0.77 | TDP1 (0.48) | KDM1ATDP1MAOBITGB3ITGA2B | |
| SCHEMBL27392263 | 0.77 | TDP1 (0.48) | KDM1ATDP1MAOBITGB3ITGA2B | |
| SCHEMBL30824929 | 0.77 | TDP1 (0.48) | KDM1ATDP1MAOBITGB3ITGA2B | |
| SCHEMBL27392313 | 0.77 | BRD4 (0.42) | BRD4 | |
| SCHEMBL27392157 | 0.72 | CHEK2 (0.44) | BRD4TDP1 | |
| SCHEMBL27392163 | 0.72 | BRD4 (0.52) | BRD4 | |
| SCHEMBL30812080 | 0.69 | BRD4 (0.41) | BRD4 | |
| SCHEMBL30812158 | 0.68 | BRD4 (0.47) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054955-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |