Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29937213 | 0.86 | SMN1; SMN2 (0.32) | KDM4EALDH1A1SMN1; SMN2EGFR | |
| SCHEMBL29306582 | 0.80 | HASPIN (0.43) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30475027 | 0.80 | NFKB1 (0.34) | — | |
| SCHEMBL29306653 | 0.79 | — | — | |
| SCHEMBL29306584 | 0.79 | HASPIN (0.42) | KDM4EALDH1A1SMN1; SMN2EGFR | |
| SCHEMBL29937137 | 0.77 | GRM4 (0.33) | — | |
| SCHEMBL24717774 | 0.77 | HASPIN (0.46) | KDM4EALDH1A1 | |
| SCHEMBL29306583 | 0.77 | MAPT (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL30015756 | 0.77 | HASPIN (0.46) | KDM4EALDH1A1 | |
| SCHEMBL24717773 | 0.75 | TP53 (0.38) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024063576-A1 | NOVEL QUINAZOLINE COMPOUND AS KRAS INHIBITOR | 일동제약(주) | 2024-03-28 | — | — | WO | disclosed |