Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29418852 | 0.86 | KRAS (0.49) | KRAS | |
| SCHEMBL29418868 | 0.86 | KRAS (0.49) | KRAS | |
| SCHEMBL30049409 | 0.83 | KRAS (0.53) | KRAS | |
| SCHEMBL30669297 | 0.83 | KRAS (0.68) | KRAS | |
| SCHEMBL30229810 | 0.81 | KRAS (0.57) | KRAS | |
| SCHEMBL29418819 | 0.79 | KRAS (0.48) | KRAS | |
| SCHEMBL29937188 | 0.78 | KRAS (0.50) | KRAS | |
| SCHEMBL31691620 | 0.77 | KRAS (0.51) | KRAS | |
| SCHEMBL30825596 | 0.77 | KRAS (0.51) | KRAS | |
| SCHEMBL30998741 | 0.76 | KRAS (0.51) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024063576-A1 | NOVEL QUINAZOLINE COMPOUND AS KRAS INHIBITOR | 일동제약(주) | 2024-03-28 | — | — | WO | disclosed |