Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218487 | 0.98 | SMN1; SMN2 (0.39) | SMN1; SMN2EZH2ALDH1A1CYP3A4CYP2B6 | |
| SCHEMBL16321589 | 0.79 | KMT2A (0.41) | SMN1; SMN2ALDH1A1CYP3A4CYP2B6GAA | |
| SCHEMBL16321588 | 0.79 | KMT2A (0.41) | SMN1; SMN2ALDH1A1CYP3A4CYP2B6GAA | |
| SCHEMBL24171772 | 0.76 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL9218473 | 0.74 | TYMP (0.38) | SMN1; SMN2ALDH1A1GAASHMT2KDM4E | |
| SCHEMBL28339794 | 0.71 | CA1 (0.46) | SMN1; SMN2EZH2ALDH1A1PKMCA1 | |
| SCHEMBL18171770 | 0.70 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1CYP3A4CYP2B6KDM4E | |
| SCHEMBL4770756 | 0.70 | CYP3A4 (0.50) | SMN1; SMN2ALDH1A1CYP3A4CYP2B6KDM4E | |
| SCHEMBL24313029 | 0.68 | CYP3A4 (0.48) | SMN1; SMN2CYP3A4CYP2B6HTT | |
| SCHEMBL4771370 | 0.68 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1CYP3A4GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119866331-A | Process for preparing brominated uracil derivatives | 安道麦阿甘有限公司 | 2025-04-22 | — | — | CN | disclosed |
| WO-2024062479-A1 | A PROCESS FOR PREPARING BROMINATED URACIL DERIVATIVES | ADAMA AGAN LTD. (IL) | 2024-03-28 | — | — | WO | disclosed |