Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 5/20 | 0.84 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.84 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.84 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.84 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.84 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.84 |
| ▸ | SLCO1A2 | P46721 | 2/20 | 0.84 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.84 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.84 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 4/20 | 0.67 |
| ▸ | ABCC2 | Q92887 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | ABCC3 | O15438 | 3/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.67 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.67 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437937 | 1.00 | ABCB11 (0.84) | ABCB11TBXA2RCHRM1PTGS1SLCO2B1 | |
| SCHEMBL437936 | 1.00 | ABCB11 (0.84) | ABCB11TBXA2RCHRM1PTGS1SLCO2B1 | |
| SCHEMBL22553370 | 1.00 | ABCB11 (0.84) | ABCB11TBXA2RCHRM1PTGS1SLCO2B1 | |
| SCHEMBL16509411 | 1.00 | ABCB11 (0.84) | ABCB11TBXA2RCHRM1PTGS1SLCO2B1 | |
| SCHEMBL18573042 | 1.00 | ABCB11 (0.84) | ABCB11TBXA2RCHRM1PTGS1SLCO2B1 | |
| SCHEMBL31171049 | 1.00 | ABCB11 (0.84) | ABCB11TBXA2RCHRM1PTGS1SLCO2B1 | |
| SCHEMBL16509382 | 0.94 | ABCB11 (0.74) | ABCB11TBXA2RCHRM1PTGS1SLCO2B1 | |
| Rifamide SCHEMBL1650471 | 0.93 | ABCB11 (0.80) | ABCB11TBXA2RCHRM1PTGS1SLCO2B1 | |
| Rifamide SCHEMBL49237 | 0.93 | ABCB11 (0.80) | ABCB11TBXA2RCHRM1PTGS1SLCO2B1 | |
| Rifamide SCHEMBL49236 | 0.93 | ABCB11 (0.80) | ABCB11TBXA2RCHRM1PTGS1SLCO2B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118873822-A | Treatment of gastrointestinal disorders with TNF inhibitors | 比奥拉治疗股份有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-110430801-B | Treatment of gastrointestinal disorders with TNF inhibitors | 比奥拉治疗股份有限公司 | 2024-04-30 | — | — | CN | disclosed |