Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | BCL6 | P41182 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | PRKDC | P78527 | 3/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27252335 | 1.00 | HSD17B10 (0.42) | HSD17B10HPGDHTTGRM4MAOB | |
| SCHEMBL29314306 | 0.87 | PIK3CA (0.39) | HSD17B10HPGDHTTGRM4MAOB | |
| SCHEMBL27252258 | 0.84 | JAK3 (0.39) | BCL6MEN1KMT2AL3MBTL1PIK3CA | |
| SCHEMBL27252269 | 0.84 | TNKS (0.40) | HSD17B10HPGDHTTGRM4BCL6 | |
| SCHEMBL27446467 | 0.84 | HSD17B10 (0.35) | HSD17B10HPGDHTTGRM4MAOB | |
| SCHEMBL27252322 | 0.79 | GSK3B (0.37) | HSD17B10HPGDHTTBCL6MEN1 | |
| SCHEMBL27263578 | 0.78 | PRKDC (0.46) | PIK3CAPRKDCMTOR | |
| SCHEMBL29311521 | 0.77 | HSD17B10 (0.57) | HSD17B10HPGDHTTMAOBBCL6 | |
| SCHEMBL30825851 | 0.76 | USP14 (0.42) | HSD17B10HPGDHTTGRM4MEN1 | |
| SCHEMBL27252120 | 0.76 | USP14 (0.42) | HSD17B10HPGDHTTGRM4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4590396-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | Astrazeneca AB (SE) | 2025-07-30 | — | — | EP | disclosed |
| WO-2024062089-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2024-03-28 | — | — | WO | disclosed |