Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.72 |
| ▸ | RAB9A | P51151 | 9/20 | 0.72 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | AGTR1 | P30556 | 7/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MITF | O75030 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30826078 | 1.00 | NPC1 (0.72) | NPC1RAB9AOPRK1KMT2AMEN1 | |
| SCHEMBL27178218 | 1.00 | NPC1 (0.72) | NPC1RAB9AOPRK1KMT2AMEN1 | |
| SCHEMBL27178211 | 1.00 | NPC1 (0.72) | NPC1RAB9AOPRK1KMT2AMEN1 | |
| SCHEMBL27178204 | 1.00 | NPC1 (0.72) | NPC1RAB9AOPRK1KMT2AMEN1 | |
| SCHEMBL30826076 | 0.85 | NPC1 (0.62) | NPC1RAB9AOPRK1KMT2AMEN1 | |
| SCHEMBL27178023 | 0.85 | NPC1 (0.62) | NPC1RAB9AOPRK1KMT2AMEN1 | |
| SCHEMBL27178031 | 0.85 | NPC1 (0.62) | NPC1RAB9AOPRK1KMT2AMEN1 | |
| SCHEMBL30826068 | 0.85 | NPC1 (0.76) | NPC1RAB9AOPRK1KMT2AMEN1 | |
| SCHEMBL27178190 | 0.85 | NPC1 (0.76) | NPC1RAB9AOPRK1KMT2AMEN1 | |
| SCHEMBL27178186 | 0.85 | NPC1 (0.76) | NPC1RAB9AOPRK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240101510-A1 | APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240101510-A1 | APYRASE INHIBITORS | APEH, DPEP1, PON1 | NPC1 2564/4885RAB9A 1387/4885OPRK1 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.