Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20382459 | 0.83 | HPGD (0.52) | SMN1; SMN2LMNAMEN1MAPTKMT2A | |
| SCHEMBL14107084 | 0.83 | HPGD (0.49) | SMN1; SMN2LMNAMEN1MAPTKMT2A | |
| SCHEMBL10650052 | 0.83 | MCL1 (0.54) | SMN1; SMN2LMNAMEN1MAPTKMT2A | |
| SCHEMBL7046014 | 0.80 | TDP1 (0.47) | SMN1; SMN2LMNAMEN1MAPTKMT2A | |
| SCHEMBL10849994 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL29731305 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL13303867 | 0.79 | MAPT (0.42) | SMN1; SMN2LMNAMEN1MAPTKMT2A | |
| SCHEMBL21718995 | 0.79 | MAPT (0.42) | SMN1; SMN2LMNAMEN1MAPTKMT2A | |
| SCHEMBL2476400 | 0.79 | MRGPRX4 (0.47) | SMN1; SMN2LMNAMEN1MAPTKMT2A | |
| SCHEMBL6283405 | 0.79 | KDM4E (0.54) | SMN1; SMN2LMNAMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4610260-A1 | ARYL HETEROCYCLIC KV1.3 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | Shanghai Shenshi Wise Technology Co., Ltd. (CN) | 2025-09-03 | — | — | EP | disclosed |
| CN-117946111-A | Aryl heterocycle Kv1.3 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-04-30 | — | — | CN | disclosed |