Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22322039 | 0.83 | TDP1 (0.50) | TDP1HPGDALDH1A1SMN1; SMN2ERN1 | |
| SCHEMBL1520406 | 0.81 | ALDH1A1 (0.47) | HPGDCA12CA1CA9ALDH1A1 | |
| SCHEMBL30826239 | 0.80 | SMN1; SMN2 (0.49) | HPGDCA12CA1CA9MAOB | |
| SCHEMBL28011522 | 0.80 | CA12 (0.46) | HPGDCA12CA1CA9ALDH1A1 | |
| SCHEMBL6561561 | 0.80 | TRIM24 (0.57) | HPGDCA12CA1CA9MAOB | |
| SCHEMBL4501693 | 0.80 | ALDH1A1 (0.54) | HPGDCA12CA1CA9ALDH1A1 | |
| SCHEMBL6931077 | 0.80 | CA12 (0.44) | HPGDCA12CA1CA9MAOB | |
| SCHEMBL6319246 | 0.79 | ERN1 (0.54) | TDP1HPGDALDH1A1GAAMAPT | |
| SCHEMBL8387418 | 0.79 | HPGD (0.44) | HPGDCA12CA1CA9GAA | |
| SCHEMBL8387413 | 0.79 | HPGD (0.44) | HPGDCA12CA1CA9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111718724-B | Reactive azobenzene main side chain liquid crystal compound and preparation method and application thereof | 国科广化(南雄)新材料研究院有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-111718724-A | Reactive azobenzene main side chain liquid crystal compound and preparation method and application thereof | 国科广化(南雄)新材料研究院有限公司 | 2020-09-29 | — | — | CN | claimed |
| CN-111718724-B | Reactive azobenzene main side chain liquid crystal compound and preparation method and application thereof | 国科广化(南雄)新材料研究院有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-111718724-A | Reactive azobenzene main side chain liquid crystal compound and preparation method and application thereof | 国科广化(南雄)新材料研究院有限公司 | 2020-09-29 | — | — | CN | disclosed |
| EP-0882029-B1 | HETEROCYCLIC DERIVATIVES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | MERCK & CO INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6090836-A | DIETETICS; ADJUSTMENT OF TRIGLYCERIDE CONCENTRATION | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |
| EP-0882029-A1 | HETEROCYCLIC DERIVATIVES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | Merck & Co., Inc. (US) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997028137-A1 | HETEROCYCLIC DERIVATIVES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |