SCHEMBL30826323

SCHEMBL30826323

COc1cc(C(c2ccc(O)c(C)c2)c2ccc(O)c(C)c2)ccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
CYP3A4 P08684 1/20 0.56
GAA P10253 2/20 0.55
BLM P54132 2/20 0.54
NFKB1 P19838 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
PMP22 Q01453 1/20 0.53
MAOB P27338 1/20 0.50
BCHE P06276 2/20 0.49
TYR P14679 2/20 0.49
ACHE P22303 2/20 0.49
SLC22A3 O75751 1/20 0.49
CYP19A1 P11511 1/20 0.47
NQO1 P15559 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
FOS P01100 1/20 0.45
TTR P02766 1/20 0.45
JUN P05412 1/20 0.45
NR3C1 P04150 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2865089 1.00 TSHR (0.56) TSHRCYP3A4GAABLMNFKB1
SCHEMBL20563424 0.91 TSHR (0.65) TSHRCYP3A4GAABLMNFKB1
SCHEMBL29695982 0.90 TSHR (0.53) TSHRCYP3A4GAABLMNFKB1
SCHEMBL2203108 0.90 TSHR (0.53) TSHRCYP3A4GAABLMNFKB1
SCHEMBL1596291 0.89 TSHR (0.62) TSHRCYP3A4GAABLMNFKB1
SCHEMBL19728205 0.88 TSHR (0.58) TSHRCYP3A4GAABLMNFKB1
SCHEMBL22452310 0.88 GAA (0.48) TSHRCYP3A4GAABLMNFKB1
SCHEMBL31516847 0.85 TSHR (0.59) TSHRCYP3A4GAABLMNFKB1
SCHEMBL29465801 0.84 TP53 (0.54) CYP3A4GAANPSR1HSD17B1HSD17B2
SCHEMBL674987 0.84 TP53 (0.54) CYP3A4GAANPSR1HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117756612-A Synthesis method of 4- [ bis (4-hydroxy-3-methylphenyl) methyl ] -2-methoxyphenol 沈阳思拓新材料技术有限公司 2024-03-26 CN claimed
CN-117756612-A Synthesis method of 4- [ bis (4-hydroxy-3-methylphenyl) methyl ] -2-methoxyphenol 沈阳思拓新材料技术有限公司 2024-03-26 CN disclosed
CN-117756612-A Synthesis method of 4- [ bis (4-hydroxy-3-methylphenyl) methyl ] -2-methoxyphenol 沈阳思拓新材料技术有限公司 2024-03-26 CN disclosed
CN-117756612-A Synthesis method of 4- [ bis (4-hydroxy-3-methylphenyl) methyl ] -2-methoxyphenol 沈阳思拓新材料技术有限公司 2024-03-26 CN disclosed