SCHEMBL30826516

SCHEMBL30826516

O=C(O)C[C@H](NC(=O)C1CCNCC1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 3/20 0.44
ITGA2B P08514 3/20 0.44
F2R P25116 2/20 0.44
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
PADI1 Q9ULC6 1/20 0.43
PADI4 Q9UM07 1/20 0.43
GABRP O00591 1/20 0.42
GABRD O14764 1/20 0.42
GABRA1 P14867 1/20 0.42
TSHR P16473 1/20 0.42
GABRB1 P18505 1/20 0.42
GABRG2 P18507 1/20 0.42
GABRB3 P28472 1/20 0.42
GABRA5 P31644 1/20 0.42
GABRA3 P34903 1/20 0.42
GABRA2 P47869 1/20 0.42
GABRB2 P47870 1/20 0.42
GABRA4 P48169 1/20 0.42
GABRE P78334 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25206156 0.88 LMNA (0.47) CA2CA4MAPTLMNATDP1
SCHEMBL25206154 0.88 LMNA (0.47) CA2CA4MAPTLMNATDP1
SCHEMBL6059411 0.83 CPN1 (0.49) PADI1PADI4GABRPGABRDGABRA1
SCHEMBL23967395 0.83 MME (0.46) ITGB3ITGA2BF2RCA2CA4
SCHEMBL7898517 0.83 MME (0.46) ITGB3ITGA2BF2RCA2CA4
SCHEMBL28910144 0.81 MME (0.45) ITGB3ITGA2BF2RCA2CA4
SCHEMBL2633261 0.76 LMNA (0.68) ITGB3ITGA2BPOLBL3MBTL1LMNA
SCHEMBL17793242 0.75 KDM4E (0.43) ITGB3ITGA2BF2RPADI1PADI4
SCHEMBL25223501 0.74 MEN1 (0.47) ITGB3ITGA2BCA2CA4ITGAV
SCHEMBL25491141 0.74 MEN1 (0.47) ITGB3ITGA2BCA2CA4ITGAV

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112105604-B Novel compounds exhibiting intestinal peptidase inhibitory activity 株式会社LG化学 2024-01-09 CN claimed
CN-112105604-B Novel compounds exhibiting intestinal peptidase inhibitory activity 株式会社LG化学 2024-01-09 CN disclosed