Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455002 | 0.86 | PRMT1 (0.49) | MAPTMEN1KMT2AABCG2AURKA | |
| SCHEMBL27878078 | 0.86 | PTPRB (0.40) | MAPTABCG2GSTP1GSTM2AURKA | |
| SCHEMBL30826628 | 0.85 | MAPT (0.47) | MAPTMEN1LMNAKMT2AGSTP1 | |
| SCHEMBL31455077 | 0.84 | ABCG2 (0.41) | MAPTMEN1KMT2AABCG2GSTP1 | |
| SCHEMBL17109515 | 0.82 | BRD4 (0.49) | MAPTMEN1KMT2AABCG2AURKA | |
| SCHEMBL31420320 | 0.82 | BRD4 (0.49) | MAPTMEN1KMT2AABCG2AURKA | |
| SCHEMBL31455363 | 0.81 | GSK3B (0.43) | MAPTMEN1KMT2AABCG2AURKA | |
| SCHEMBL25385291 | 0.80 | ABCG2 (0.41) | MAPTMEN1KMT2AABCG2AURKA | |
| SCHEMBL30574901 | 0.80 | ABCG2 (0.41) | MAPTMEN1KMT2AABCG2AURKA | |
| SCHEMBL31420343 | 0.80 | PRMT1 (0.41) | MAPTMEN1KMT2AABCG2AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024064026-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-03-28 | — | — | WO | disclosed |