Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455077 | 0.89 | ABCG2 (0.41) | PRMT1BRD4ABCG2MEN1KMT2A | |
| SCHEMBL31420343 | 0.88 | PRMT1 (0.41) | PRMT1BRD4BCL2BECN1ABCG2 | |
| SCHEMBL31455107 | 0.88 | BRD9 (0.41) | PRMT1BRD4BCL2BECN1MEN1 | |
| SCHEMBL17109515 | 0.87 | BRD4 (0.49) | BRD4ABCG2MEN1KMT2AMAPT | |
| SCHEMBL31420320 | 0.87 | BRD4 (0.49) | BRD4ABCG2MEN1KMT2AMAPT | |
| SCHEMBL31455106 | 0.87 | SYK (0.40) | PRMT1BCL2BECN1ABCG2MEN1 | |
| SCHEMBL31455545 | 0.87 | ABCG2 (0.41) | PRMT1BRD4BCL2BECN1ABCG2 | |
| SCHEMBL30826679 | 0.86 | MAPT (0.41) | PRMT1BRD4ABCG2MEN1KMT2A | |
| SCHEMBL25385291 | 0.85 | ABCG2 (0.41) | ABCG2MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL30574901 | 0.85 | ABCG2 (0.41) | ABCG2MEN1KMT2AMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |