Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.44 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.44 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.44 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.44 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.44 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 3/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30826663 | 0.89 | TUBB1 (0.45) | ALDH1A1ACVR1BTGFBR1ACVR1KCNH2 | |
| Hydrochloric Acid SCHEMBL27302123 | 0.81 | TLR9 (0.53) | ACVR1BTGFBR1ACVR1KCNH2ROCK1 | |
| SCHEMBL16519580 | 0.80 | HRH1 (0.46) | ACVR1BTGFBR1ACVR1KCNH2ROCK1 | |
| SCHEMBL13362130 | 0.80 | ALDH1A1 (0.54) | ALDH1A1ACVR1BTGFBR1ACVR1KCNH2 | |
| SCHEMBL12311802 | 0.80 | ACVR1B (0.51) | ACVR1BTGFBR1ACVR1KCNH2ROCK1 | |
| SCHEMBL2005106 | 0.79 | HRH3 (0.55) | ALDH1A1KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL23361975 | 0.79 | HRH1 (0.45) | ROCK1ROCK2PRKACAPRKCDPRKG1 | |
| Hydrochloric Acid SCHEMBL23086663 | 0.79 | HPGD (0.47) | ROCK1ROCK2PRKACAPRKCDPRKG1 | |
| SCHEMBL2004982 | 0.78 | HRH3 (0.54) | ALDH1A1KCNH2HRH3 | |
| SCHEMBL8666130 | 0.77 | ALDH1A1 (0.50) | ALDH1A1ACVR1BTGFBR1ACVR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024064026-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-03-28 | — | — | WO | disclosed |