Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 20/20 | 0.76 |
| ▸ | CASP3 | P42574 | 18/20 | 0.76 |
| ▸ | CASP7 | P55210 | 18/20 | 0.76 |
| ▸ | CDK1 | P06493 | 3/20 | 0.67 |
| ▸ | CDK2 | P24941 | 3/20 | 0.67 |
| ▸ | GSK3B | P49841 | 3/20 | 0.67 |
| ▸ | CDK7 | P50613 | 3/20 | 0.67 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.67 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828123 | 1.00 | CDK9 (0.76) | CDK9CASP3CASP7CDK1CDK2 | |
| SCHEMBL27382665 | 0.87 | CDK9 (1.00) | CDK9CASP3CASP7CDK1CDK2 | |
| SCHEMBL27382666 | 0.85 | CDK9 (0.66) | CDK9CASP3CASP7CDK1CDK2 | |
| SCHEMBL27369600 | 0.84 | CDK9 (0.80) | CDK9CASP3CASP7CDK1CDK2 | |
| SCHEMBL30394395 | 0.75 | CDK9 (0.78) | CDK9CASP3CASP7CDK1CDK2 | |
| SCHEMBL27371590 | 0.66 | CDK9 (0.63) | CDK9CASP3CASP7CCNT1 | |
| SCHEMBL29431255 | 0.64 | CDK9 (0.54) | CDK9CASP3CASP7CDK1CDK2 | |
| SCHEMBL3414528 | 0.63 | IKBKB (0.82) | CDK9CASP3CASP7CDK1CDK2 | |
| SCHEMBL13014313 | 0.63 | IKBKB (0.82) | CDK9CASP3CASP7CDK1CDK2 | |
| SCHEMBL3412704 | 0.63 | IKBKB (0.82) | CDK9CASP3CASP7CDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054953-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |