Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | XPO1 | O14980 | 1/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24738932 | 0.91 | GAA (0.45) | RAB9APTGS1NPC1GAAPOLB | |
| SCHEMBL282866 | 0.88 | DEGS1 (0.51) | RAB9APTGS1NPC1GAAPOLB | |
| SCHEMBL31000170 | 0.87 | GAA (0.42) | RAB9APTGS1NPC1GAAPOLB | |
| SCHEMBL31706891 | 0.86 | GAA (0.44) | RAB9APTGS1NPC1GAAPOLB | |
| SCHEMBL15600409 | 0.86 | GAA (0.70) | RAB9APTGS1NPC1GAAPOLB | |
| SCHEMBL23582651 | 0.85 | GSK3B (0.43) | RAB9APTGS1NPC1GAAPOLB | |
| SCHEMBL23582524 | 0.83 | HDAC1 (0.41) | RAB9APTGS1NPC1GAAPOLB | |
| SCHEMBL31357577 | 0.83 | HDAC1 (0.41) | RAB9APTGS1NPC1GAAPOLB | |
| SCHEMBL31705856 | 0.82 | GAA (0.55) | RAB9APTGS1NPC1GAAPOLB | |
| SCHEMBL31292326 | 0.82 | HDAC1 (0.41) | RAB9APTGS1NPC1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561061-A | Combination of 3- (imidazol-4-yl) -4- (amino) -benzenesulfonamide TEAD inhibitors with EGFR inhibitors and/or MEK inhibitors for the treatment of lung cancer | 医肯纳肿瘤学公司 | 2024-02-13 | — | — | CN | disclosed |