SCHEMBL30828516

SCHEMBL30828516

[2H]c1cc(C)cc(C)c1C=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.41
TSHR P16473 1/20 0.41
ERN1 O75460 2/20 0.40
GRIA1 P42261 1/20 0.38
GRIA2 P42262 1/20 0.38
GRIA3 P42263 1/20 0.38
GRIA4 P48058 1/20 0.38
SRC P12931 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 1/20 0.37
MPI P34949 1/20 0.37
GAA P10253 1/20 0.35
NPC1 O15118 1/20 0.35
PKM P14618 1/20 0.35
RAB9A P51151 1/20 0.35
CYP2A6 P11509 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95501 0.79 ALDH1A1 (0.52) ALDH1A1TSHRERN1GRIA1GRIA2
SCHEMBL29437223 0.79 ALDH1A1 (0.52) ALDH1A1TSHRERN1GRIA1GRIA2
SCHEMBL8434668 0.72 ALDH1A1 (0.50) ALDH1A1TSHRERN1GRIA1GRIA2
M-Xylene SCHEMBL7774600 0.72 ALDH1A1 (0.50) ALDH1A1TSHRERN1GRIA1GRIA2
SCHEMBL30828533 0.71
SCHEMBL2884919 0.70 GRIA1 (0.56) ALDH1A1TSHRERN1GRIA1GRIA2
SCHEMBL268706 0.70 ALDH1A1 (0.52) ALDH1A1TSHRERN1GRIA1GRIA2
P-Xylene SCHEMBL7770805 0.68 ALDH1A1 (0.50) ALDH1A1TSHRERN1GRIA1GRIA2
SCHEMBL28109967 0.68 ALDH1A1 (0.50) ALDH1A1TSHRERN1GRIA1GRIA2
SCHEMBL18128766 0.68 GRIA1 (0.54) ALDH1A1TSHRERN1GRIA1GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113651663-B Preparation method of deuterated aromatic carbonyl compound 浙大宁波理工学院 2024-03-29 CN disclosed