SCHEMBL30828541

SCHEMBL30828541

O=C1CSc2ncc(N3C[C@@H](CO)OC3=O)nc2N1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 7/20 0.57
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
CALML3 P27482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21409423 1.00 KCNH2 (0.57) KCNH2MAOAMAOBCALML3
SCHEMBL21409424 1.00 KCNH2 (0.57) KCNH2MAOAMAOBCALML3
SCHEMBL25024697 1.00 KCNH2 (0.57) KCNH2MAOAMAOBCALML3
SCHEMBL21428648 0.90 KCNH2 (0.54) KCNH2
SCHEMBL23084963 0.90 KCNH2 (0.56) KCNH2
SCHEMBL30393217 0.90 KCNH2 (0.54) KCNH2
SCHEMBL22490605 0.90 KCNH2 (0.54) KCNH2
SCHEMBL25024256 0.90 KCNH2 (0.54) KCNH2
SCHEMBL30382251 0.90 KCNH2 (0.54) KCNH2
SCHEMBL25024698 0.85 KCNH2 (0.50) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250136618-A1 ANTIBIOTIC PYRAZINOTHIAZINE DERIVATIVES AND PROCESS OF PREPARATION THEREOF BUGWORKS RESEARCH INDIA PVT LTD (IN) 2025-05-01 US disclosed
CN-117794939-A Antibiotic pyrazinothiazine derivatives and process for their preparation 巴格沃克斯研究印度私人有限公司 2024-03-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136618-A1 ANTIBIOTIC PYRAZINOTHIAZINE DERIVATIVES AND PROCESS OF PREPARATION THEREOF TFPI, CLPP, PLK4 KCNH2 3154/4885MAOA 170/4885MAOB 102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.