Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.85 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.85 |
| ▸ | POLB | P06746 | 3/20 | 0.84 |
| ▸ | MAPT | P10636 | 2/20 | 0.84 |
| ▸ | GAA | P10253 | 1/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | MITF | O75030 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | NT5E | P21589 | 1/20 | 0.71 |
| ▸ | JAK2 | O60674 | 1/20 | 0.70 |
| ▸ | TYK2 | P29597 | 1/20 | 0.70 |
| ▸ | STAT3 | P40763 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.63 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.63 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828582 | 1.00 | KDM4E (0.85) | KDM4EL3MBTL1POLBMAPTGAA | |
| SCHEMBL23999623 | 1.00 | KDM4E (0.85) | KDM4EL3MBTL1POLBMAPTGAA | |
| SCHEMBL30828563 | 0.95 | POLB (0.77) | KDM4EL3MBTL1POLBMAPTGAA | |
| SCHEMBL23999788 | 0.93 | POLB (0.74) | KDM4EL3MBTL1POLBMAPTGAA | |
| SCHEMBL27193253 | 0.93 | POLB (0.74) | KDM4EL3MBTL1POLBMAPTGAA | |
| SCHEMBL14716526 | 0.92 | KDM4E (1.00) | KDM4EL3MBTL1POLBMAPTGAA | |
| SCHEMBL12240504 | 0.92 | POLB (1.00) | KDM4EL3MBTL1POLBMAPTGAA | |
| SCHEMBL29393952 | 0.91 | JAK2 (0.86) | KDM4EL3MBTL1POLBMAPTGAA | |
| SCHEMBL23999634 | 0.89 | POLB (0.68) | KDM4EL3MBTL1POLBMAPTGAA | |
| SCHEMBL27193241 | 0.89 | POLB (0.88) | KDM4EL3MBTL1POLBMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | SAINT LOUIS UNIVERSITY (US) | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | ABCC1, ARG1, SLC11A2 | KDM4E 854/4885L3MBTL1 2234/4885POLB 1009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.