Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | PNMT | P11086 | 2/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3617955 | 1.00 | GBA1 (0.48) | GBA1PNMTACP3AOC3MEN1 | |
| SCHEMBL3446697 | 1.00 | GBA1 (0.48) | GBA1PNMTACP3AOC3MEN1 | |
| SCHEMBL3489363 | 1.00 | GBA1 (0.48) | GBA1PNMTACP3AOC3MEN1 | |
| SCHEMBL30353858 | 1.00 | GBA1 (0.48) | GBA1PNMTACP3AOC3MEN1 | |
| Hydrochloric Acid SCHEMBL382469 | 0.98 | GBA1 (0.47) | GBA1PNMTACP3AOC3MEN1 | |
| Hydrochloric Acid SCHEMBL1440815 | 0.98 | GBA1 (0.47) | GBA1PNMTACP3AOC3MEN1 | |
| Hydrochloric Acid SCHEMBL1440813 | 0.98 | GBA1 (0.47) | GBA1PNMTACP3AOC3MEN1 | |
| Malonic Acid SCHEMBL17958979 | 0.88 | MEN1 (0.46) | GBA1ACP3MEN1KMT2ALMNA | |
| SCHEMBL25269085 | 0.84 | PNMT (0.47) | GBA1PNMTACP3AOC3MEN1 | |
| SCHEMBL382070 | 0.84 | PNMT (0.47) | GBA1PNMTACP3AOC3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584265-A1 | NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF | Cambridge Enterprise Limited (GB) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024052690-A1 | NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-03-14 | — | — | WO | disclosed |