⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4217235 | 1.00 | — | — | |
| SCHEMBL3421681 | 0.75 | — | — | |
| SCHEMBL1428398 | 0.75 | — | — | |
| SCHEMBL1187131 | 0.75 | — | — | |
| SCHEMBL788493 | 0.75 | — | — | |
| SCHEMBL30394341 | 0.75 | — | — | |
| SCHEMBL850260 | 0.75 | — | — | |
| SCHEMBL30151389 | 0.75 | — | — | |
| SCHEMBL1586143 | 0.75 | — | — | |
| Ammonia Solution, Strong SCHEMBL28432870 | 0.73 | LMNA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794529-A | POLO-like kinase 4 inhibitors | 欧瑞克制药公司 | 2024-03-29 | — | — | CN | disclosed |